Grey's Anatomy season 22 offers up more high-stakes drama

The season chronicled another chapter of life, love, and medicine at Grey Sloan Memorial for Meredith Grey and her fellow surgeons

Few shows balance pulse-pounding cases with heartfelt character moments like Grey's Anatomy, and Season 22, anchored by Ellen Pompeo’s enduring performance, delivered even more of the intense hospital drama that fans love. Longtime favourites and fresh faces alike joined the season, testing the limits of both their scalpel skills and personal bonds.

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When did Grey's Anatomy season 22 premiere?

Season 22 of the long-running series premiered 10 October 2025 on Disney+ in the UK.

What’s the plot of Grey's Anatomy season 22?

The high-intensity medical drama follows Dr. Meredith Grey (Ellen Pompeo) and the dedicated staff of Grey Sloan Memorial Hospital as they make life-or-death decisions every day. Season 22 follows on from the explosive finale of the previous season and continues the show’s signature blend of complex surgeries, evolving relationships, and ethical dilemmas that refuse to be defined in black and white.

Who are the cast and characters in Grey's Anatomy season 22?

• Ellen Pompeo as Dr. Meredith Grey

• Chandra Wilson as Dr. Miranda Bailey

• James Pickens Jr. as Dr. Richard Webber

• Kevin McKidd as Dr. Owen Hunt

• Caterina Scorsone as Dr. Amelia Shepherd

• Camilla Luddington as Dr. Jo Wilson

• Kim Raver as Dr. Teddy Altman

• Chris Carmack as Dr. Atticus “Link” Lincoln

• Anthony Hill as Dr. Winston Ndugu

• Jason George as Dr. Ben Warren

• Alexis Floyd as Simone Griffith

• Harry Shum Jr. as Benson “Blue” Kwan

• Adelaide Kane as Jules Millin

• Niko Terho as Lucas Adams

• Trevor Jackson as Wes

Who’s behind Grey's Anatomy season 22?

Season 22 is steered by executive producer and showrunner Meg Marinis alongside creator Shonda Rhimes, executive producers Betsy Beers, Mark Gordon, Ellen Pompeo, Debbie Allen, Zoanne Clack, and Mark Driscoll.

Where was Grey's Anatomy season 22 filmed?

Production took place in Los Angeles, California.

Will there be a Season 23 of Grey’s Anatomy?

The doctors are scrubbing back in! Grey’s Anatomy returns for season 23 on ABC in the USA on 15 October 2026. Following an emotional season 22 finale, the next chapter at Grey Sloan Memorial is just around the corner.

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