Grey's Anatomy Season 22 Offers Up More High-Stakes Drama
by Explore Disney+ Contributor
October 14, 2025
The season chronicled another chapter of life, love, and medicine at Grey Sloan Memorial for Meredith Grey and her fellow surgeons
Few shows balance pulse-pounding cases with heartfelt character moments like Grey's Anatomy, and Season 22, anchored by Ellen Pompeo’s enduring performance, delivered even more of the intense hospital drama that fans love. Longtime favorites and fresh faces alike joined the season, testing the limits of both their scalpel skills and personal bonds.
Add Grey's Anatomy to Watchlist (login required) or learn more on Hulu.com
When did Grey's Anatomy Season 22 premiere?
Season 22 of the medical show premiered on October 9, 2025. The full season is streaming now on Hulu and Hulu on Disney+ for bundle subscribers.*
What’s the plot of Grey's Anatomy Season 22?
The high-intensity medical drama follows Dr. Meredith Grey (Ellen Pompeo) and the dedicated staff of Grey Sloan Memorial Hospital as they make life-or-death decisions every day. Season 22 follows on from the explosive finale of the previous season and continues the show’s signature blend of complex surgeries, evolving relationships, and ethical dilemmas that refuse to be defined in black and white.
Who are the cast and characters in Grey's Anatomy Season 22?
Ellen Pompeo plays Dr. Meredith Grey
Chandra Wilson plays Dr. Miranda Bailey
James Pickens Jr. plays Dr. Richard Webber
Kevin McKidd plays Dr. Owen Hunt
Caterina Scorsone plays Dr. Amelia Shepherd
Camilla Luddington plays Dr. Jo Wilson
Kim Raver plays Dr. Teddy Altman
Chris Carmack plays Dr. Atticus “Link” Lincoln
Anthony Hill plays Dr. Winston Ndugu
Jason George plays Dr. Ben Warren
Alexis Floyd plays Simone Griffith
Harry Shum Jr. plays Benson “Blue” Kwan
Adelaide Kane plays Jules Millin
Niko Terho plays Lucas Adams
Trevor Jackson plays Wes
Who’s behind Grey's Anatomy Season 22?
Executive producer and showrunner Meg Marinis steers Season 22 alongside creator Shonda Rhimes, executive producers Betsy Beers, Mark Gordon, Ellen Pompeo, Debbie Allen, Zoanne Clack, and Mark Driscoll.
Where was Grey's Anatomy Season 22 filmed?
Production took place in Los Angeles, California.
Will there be a Season 23 of Grey’s Anatomy?
The doctors are scrubbing back in! Grey’s Anatomy returns for Season 23 on October 15, 2026, on ABC, with new episodes streaming the next day on Hulu and Hulu on Disney+ for bundle subscribers.* Following an emotional Season 22 finale, the next chapter at Grey Sloan Memorial is just around the corner.
Add Grey's Anatomy to Watchlist (login required) or learn more on Hulu.com
*Available for U.S. residents, 18+ only. Location data required to watch certain content. Select Hulu content available via Disney+; additional content only available via Hulu app. Offer valid for eligible subscribers only. Subject to Disney+ and ESPN Subscriber Agreement. Additional terms, app feature and device restrictions apply. For more information visit the Disney+ Help Center. © 2026 Disney and its related entities.
